'Pouring out the vials upon the earth, which contained the plagues,' in Revelation 16:1, signifies influx of the reformed into the church, or into people who study and receive the doctrine of justification by faith alone.

(Referencat: Apocalypse Explained 16; Apocalypse Revealed 676)

2623. 'A son' means the Divine Rational. This is clear from the meaning of 'a son'. In the internal sense of the Word 'a son' means truth, 489, 491, 533; and because truth is the principal element in the rational, 2072, 2189, 'a son' also means the rational. But here the Divine Rational is meant in which the principal element is good. 'Isaac' too, to whom 'a son' refers, represents this good, as will be shown further on.