'Look not back behind thee,' as in Genesis 19:17, means that Lot, who represents the good of charity, should not look to matters of doctrine. 'To look up,' is to look to celestial things. In Genesis 18:22, looking signifies thinking because seeing denotes understanding.

(Referencat: Arcana Coelestia 2245)

In Revelation 4:7, a face like a man signifies affection of truth, and, more interiorly, wisdom. (Apocalypse Revealed 243, Apocalypse Explained 280)