284. And they were full of eyes within. That this signifies the Divine providence and guardianship, is evident from the signification of eyes, when said of the Lord, as being His Divine providence (concerning which see above, n. 68 152). The reason why guardianship is also signified is that cherubim have also that signification (n. 277).

Four signifies celestial good, and six, spiritual good; for four signifies conjunction, and intimate conjunction with the Lord occurs when we love Him; but six signifies communication, and communication with the Lord is manifested by charity towards the neighbor.

(References: Apocalypse Explained 283)