'Pouring out the vials upon the earth, which contained the plagues,' in Revelation 16:1, signifies influx of the reformed into the church, or into people who study and receive the doctrine of justification by faith alone.

(References: Apocalypse Explained 16; Apocalypse Revealed 676)

'The smitten' signify people who are oppressed by the falsities of ignorance.

(References: Apocalypse Explained 357)