'Pouring out the vials upon the earth, which contained the plagues,' in Revelation 16:1, signifies influx of the reformed into the church, or into people who study and receive the doctrine of justification by faith alone.

(References: Apocalypse Explained 16; Apocalypse Revealed 676)

In 2 Kings 1:2; Psalm 38:7; Exodus 15:26; Luke 6:17, this signifies temptations, and corresponds with the state of the man's spirit. (Arcana Coelestia 5711)

In Deuteronomy 7:15, this signifies the evils which assail people in faith separate from charity, and so in a life of evil. (Arcana Coelestia 8364)

In Matthew 4:24, disease or illness signifies various kinds of evils and falsities infesting the church and the human race, which if allowed to continue, would have induced spiritual death. (Arcana Coelestia 8364) 'Pestilence' denotes the vastation of good and truth.

(References: Arcana Coelestia 7102)