'Pouring out the vials upon the earth, which contained the plagues,' in Revelation 16:1, signifies influx of the reformed into the church, or into people who study and receive the doctrine of justification by faith alone.

(Референци: Apocalypse Explained 16; Apocalypse Revealed 676)

387. And with death, signifies the consequent extinction of spiritual life. This is evident from the signification of "death," as being the extinction of spiritual life (See above, n. 78, 186). That this is what "death" here signifies is evident from the series of things in the internal sense; for it is said that "there was given unto them power to kill with sword, with famine, and with death;" and "sword" signifies falsity destroying truth, "famine" the deprivation of the knowledges of truth and good; thence "death" signifies the extinction of spiritual life; for where falsity reigns, and where there are no knowledges of truth and good, there is no spiritual life, for spiritual life is acquired by means of the knowledges of truth and good applied to the uses of life. For man is born into all evil and falsity from evil; he is therefore born also into an entire ignorance of all spiritual knowledges; therefore in order that he may be led away from the evils and consequent falsities into which he is born, and be led into the life of heaven and be saved, he must needs acquire the knowledges of truth and good, by means of which he can be led into spiritual life and become spiritual. From this series of things in the internal sense it is evident that "death" here signifies the extinction of spiritual life; this is meant, too, by spiritual death.