250. Verse 15. And I will put enmity between thee and the woman, and between thy seed and her seed; He shall trample upon thy head, and thou shalt bruise His heel. Everyone is aware that this is the first prophecy of the Lord’s advent into the world; it appears indeed clearly from the words themselves, and therefore from them and from the prophets even the Jews knew that a Messiah was to come. Hitherto however no one has understood what is specifically meant by the “serpent” the “woman” the “serpent’s seed” the “woman’s seed” the “head of the serpent which was to be trodden upon” and the “heel which the serpent should bruise.” They must therefore be explained. By the “serpent” is here meant all evil in general, and specifically the love of self; by the “woman” is meant the church; by the “seed of the serpent” all infidelity; by the “seed of the woman” faith in the Lord; by “He” the Lord Himself; by the “head of the serpent” the dominion of evil in general, and specifically that of the love of self; by to “trample upon” depression, so that it should “go upon the belly and eat dust;” and by the “heel” the lowest natural (as the corporeal), which the serpent should “bruise.”

251. The reason 'the serpent' is used to mean all evil in general and self-love in particular is that all evil has originated in sensory evidence and also factual knowledge, which are what the serpent meant first. Consequently it now means evil itself, of every kind, and in particular self-love, or hatred of the neighbour and the Lord, which is the same as self-love. Because this evil or hatred is manifold, there being many genera of it and even more species, it is referred to in the Word by means of different kinds of serpents, such as snakes, adders, asps, haemorrhes, presters or fiery serpents, flying as well as creeping serpents, and vipers.

[2] These vary according to differences of poison, which is hatred, as in Isaiah,

Rejoice not, O Philistia, all of you, that the rod which smites you has been broken, for from the serpent's root will come forth an adder, and its fruit will be a flying prester. Isaiah 14:29.

'Serpent's root' means sensory evidence and factual knowledge, 'adder' evil that is the outcome of falsity arising from these, 'flying prester' desire which is the product of self-love. Similar references appear in the following from the same Prophet,

They hatch adder's eggs, and weave spider's webs; he who eats their eggs dies, and when it is pressed out a viper is hatched. Isaiah 59:5.

The serpent mentioned here in Genesis is in the Book of Revelation called 'the great fiery-red dragon', and 'the serpent of old', and also 'the devil and satan who leads the whole world astray', Revelation 12:3, 9; 20:2. Here and elsewhere devil is never used to mean some devil who is the prince of the rest but the entire crew of evil spirits, and evil itself.