In Revelation 6:1, this signifies attention and perception. (Apocalypse Explained 354)

8555. After this the subject is the conflict of falsity arising from evil with the truth and good of faith. That conflict is represented by the battle which Amalek fought against Israel. The fact that those who have the truth and good of faith within them are winning when they look up to the Lord, and losing when they look down, is represented by the children of Israel, who were winning as long as Moses kept his hands raised up, but losing whenever he let them down.