When the Bible talks about someone being comforted or consoled, it generally means that they are being offered ideas that will help bring them to a more peaceful spiritual state, whether it is a new state or the restoration of one that had been under attack. It's interesting; we tend to think of comforting someone as an emotional thing, offering our own feelings to help them feel better. But the Writings say that the spiritual meaning of 'comfort' is actually more intellectual, coming when a person gains new true ideas.

In Genesis 5:29, this signifies doctrine whereby what was perverted may be restored. (Arcana Coelestia 531)

In Genesis 27:42, this signifies intent to invert the current spiritual state.

2996. Though in this world a very deep arcanum, nothing is better known in the next life, known even to every spirit, than the truth that all things in the human body have a correspondence with things in heaven. So true is this that not even the smallest part in the human body fails to have something spiritual and celestial, or what amounts to the same, the heavenly communities, corresponding to it. For heavenly communities exist according to all the genera and species of spiritual and celestial things; indeed they exist in such order that all of them together represent one human being. They do so in every single detail of the human being, both interior and exterior. This is why heaven considered as a whole is also called the Grand Man, and why so many times already one community has been spoken of as belonging to this part of the body, another community to that, and so on. The reason why heaven is described in this way is that the Lord is the only Man and heaven represents Him. Also it is Divine Good and Truth received from Him that constitute heaven, and therefore as angels are in heaven they' are said to be in the Lord. Those in hell however are outside of that Grand Man. These correspond to filth and also to things full of disease.