Genesis 48:16

¹⁶ The angel who hath redeemed me from all evil, bless the lads; and let my name be named on them, and the name of my fathers Abraham and Isaac: and let them grow into a multitude in the midst of the earth.

Issue

In Leviticus 15:4, 'to be affected with an issue' or refers to people in natural love separate from spiritual love.