'To be avenged seventy and seven fold' denotes damnation.

In Genesis 4:15, vengeance signifies a sacrilege, and condemnation for it. (Arcana Coelestia 392)

In Deuteronomy 32:35, this signifies the genuine truth that the Lord is love and mercy itself. (Doctrine Regarding Sacred Scripture 94)

In Psalm 94:1, this signifies judgment on the Jews because they had destroyed the church. (The Inner Meaning of the Prophets and Psalms 344)

In Psalm 99:8, this signifies that the Lord is the Redeemer although it appears that He punishes. (The Inner Meaning of the Prophets and Psalms 349; Doctrine Regarding Sacred Scripture 94)

In Isaiah 59:17, this signifies the truths by which the Lord fought with the hells. (Apocalypse Explained 395[13])

In Isaiah 34:8, this signifies the Last Judgment and the condemnation of people who, by falsities and evils, have destroyed the truths of the church. (Apocalypse Explained 850[16])

(Odkazy: Arcana Coelestia 432-444, Genesis 4:24)

392. Verse 15 And Jehovah said to him, Therefore anyone killing Cain, vengeance will be taken on him sevenfold. And Jehovah put a sign on Cain, lest anyone finding him should strike him. 'Anyone killing Cain, vengeance will be taken on him sevenfold' means that to violate faith thus separated was utterly forbidden. 'Jehovah put a sign on Cain, lest anyone should strike him' means that the Lord distinguished faith in a special way to ensure its preservation.