'To smite' signifies condemnation.

'To smite the earth with every plague as often as they will,' as in Revelation 11:6, signifies the destruction of the church by all kinds of evils and falsities.

Among the ancients, who lived in an age of representatives and meaningful signs, 'to smite the mother with the children' was a proverbial expression meaning the destruction of the Church and of everything that belonged to the Church either in general, or in particular with anyone who in himself is a Church. 'Mother' was used to mean the Church, and 'children' or 'sons,' truths which belonged to the Church. So 'to smite the mother with the children' means to perish completely, as a person also perishes completely when the Church and what belongs to the Church perishes in him, or when the affection for truth, which is the meaning of 'mother' and constitutes the Church in a person, is destroyed. 

'To smite,' as in Genesis 32:8, signifies destruction.

In Genesis 14:15, this signifies vindication.

(Odkazy: Arcana Coelestia 7871)

7871. 'And will strike all the firstborn in the land of Egypt' means the damnation of those governed by faith separated from charity. This is clear from the meaning of 'striking' as damnation, for striking is killing or putting to death, and 'death' in the spiritual sense means damnation, see 6119; from the meaning of 'the firstborn' - when used in reference to the Egyptians, who represent those steeped in falsities arising from evil - as faith separated from charity, 3325, 7039, 7766, 7778, 7779. In the genuine sense the expression 'the firstborn', when it describes a feature of the spiritual Church, means faith that is wedded to charity, see 367, 2435, 3325, 3494, 6344, 7035; therefore in the contrary sense 'the firstborn' is faith devoid of charity.