In Genesis 42:38, this signifies the last of the church. (Arcana Coelestia 5550)

In Genesis 44:29, this signifies spiritual good will perish, and so the internal of the church. (Arcana Coelestia 5832)

In Isaiah 46:4, this signifies education even to old age. (Apocalypse Explained 710[3])

5887. 'And now, do not be grieved' means anxiety in the heart or will. This is clear from the meaning of 'grief' as anxiety, existing indeed in the heart or will. For the words that immediately follow 'do not have any anger in your eyes' mean sadness in the spirit or understanding. The expressions 'in the heart or will' and 'in the spirit or understanding' are used because 'the heart' has reference through correspondence to desires in the will, for it has reference to what is celestial, which is the good of love. But 'the spirit', which is associated with the lungs, has reference to ideas in the understanding, for it has reference to what is spiritual, which is the truth of faith, see 3635, 3883-3896.