Hands in the Bible represent power, the force with which things are put into action. To be specific, they represent the power of spiritual good -- which is the love of others and serving others -- expressed through spiritual truth -- which is an understanding and knowledge of what it is to love and serve others. This is in contrast to the feet, which represent power on the natural level, and a “rod,” which represents the power of the hand passed down into external or natural ideas. In a few cases in the Bible, hands also represent communication and a drawing together. This is true when people lift their hands to heaven or to Jehovah, and also when the Lord touches children or touches people to heal them.

6425. 'By the hands of the powerful Jacob' means received from the almighty power of the Lord's Divine Human. This is clear from the meaning of 'the hands' as power, dealt with immediately above in 6424, and in the highest sense, in which the Lord is the subject, as almighty power, 878, 3387, 4592, 4933 (end); and from the meaning of 'the powerful Jacob' as the Lord's Divine Natural, thus His Divine Human, 1893, 3305, 3576, 3599, 4286, 4538, 6098, 6185, 6276. That the Lord is the One who is meant by 'the powerful Jacob' is also evident in David,

He who swore to Jehovah made a vow to the powerful Jacob, If I enter the tent of my house . . . until I find a place for Jehovah, the dwelling-places of the powerful Jacob. Psalms 132:2-3, 5.

And in Isaiah,

That all flesh may know that I Jehovah am your Saviour and your Redeemer, the powerful Jacob. Isaiah 49:26.

In the same prophet,

Hear, O Jacob my servant, and Israel whom I have chosen. I will pour out My spirit upon your seed, and My blessing upon your sons. This one will say, I am Jehovah's, and that one will call himself by the name of Jacob, and another will write with his hand, Jehovah's, and surname himself by the name of Israel. Isaiah 44:1-3, 5.

In the highest sense 'Israel' too means the Lord, in Hosea,

When Israel was a boy I loved him, and out of Egypt I called my son. Hosea 11:1.

The fact that it is the Lord who is meant here by 'Israel' is clear in Matthew,

Joseph went with the boy into Egypt, so that what had been said by the prophet might be fulfilled, Out of Egypt have I called My son. Matthew 2:14-15.