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Horch! Ein Geschrei aus Horonaim: Verheerung und große Zertrümmerung!
When the Bible talks about someone being comforted or consoled, it generally means that they are being offered ideas that will help bring them to a more peaceful spiritual state, whether it is a new state or the restoration of one that had been under attack. It's interesting; we tend to think of comforting someone as an emotional thing, offering our own feelings to help them feel better. But the Writings say that the spiritual meaning of 'comfort' is actually more intellectual, coming when a person gains new true ideas.
In Genesis 5:29, this signifies doctrine whereby what was perverted may be restored. (Arcana Coelestia 531)
In Genesis 27:42, this signifies intent to invert the current spiritual state.
197. With the most ancient people, who were celestial, a serpent meant being completely watchful, and so also meant their sensory perception by means of which they were to show vigilance to avoid being harmed by the evil. This is clear from the Lord's words to His disciples,
Behold, I send you out as sheep in the midst of wolves; so be shrewd as serpents and simple as doves. Matthew 10:16.
And also 'the bronze serpent' which was raised up in the wilderness and which meant the Lord's Sensory Perception. He alone is Celestial Man, and He alone is completely watchful and provides for everybody. Whoever beheld it therefore was delivered.