Pour out
'Pouring out the vials upon the earth, which contained the plagues,' in Revelation 16:1, signifies influx of the reformed into the church, or into people who study and receive the doctrine of justification by faith alone.
(Odkazy: Apocalypse Explained 16; Apocalypse Revealed 676)
The living creatures not resting day or night
In Revelation 4:8, this signifies that what the Word continually teaches is that the Lord Jesus Christ alone is God, and is alone to be worshipped. (Apocalypse Explained 285, Apocalypse Revealed 247)