'Pouring out the vials upon the earth, which contained the plagues,' in Revelation 16:1, signifies influx of the reformed into the church, or into people who study and receive the doctrine of justification by faith alone.

(Odkazy: Apocalypse Explained 16; Apocalypse Revealed 676)

322. The four animals and the four and twenty elders fell down before the Lamb, signifies the acknowledgment and consequent glorification of the Lord by the angels of the higher heavens. This is evident from the signification of "the four animals and the four and twenty elders," as being, in general, the whole heaven, but especially the inmost heaven, consequently the angels of the higher heavens (of which see above, n. 313; here especially the angels of those heavens, because in what follows there is glorification by the angels of the lower heavens. Also from the signification of "fell down before the Lamb," as being acknowledgment from a humble heart. That "to fall down" signifies humiliation, and in that state acknowledgment of heart, see above n. 290. Acknowledgment of the Lord's Divine Human is clearly meant, for that is signified by "the Lamb" (See above, n. 314). What the higher heavens are, and what the lower heavens are, shall be told in a few words. There are three heavens: the third or inmost heaven is where the angels are who are in celestial love; the second or middle heaven is where the angels are who are in spiritual love; the first or ultimate heaven is where the angels are who are in spiritual-natural love. The third or inmost heaven is conjoined with the second or middle by intermediate angels, who are called celestial-spiritual and spiritual-celestial angels; these intermediate angels, together with the angels of the third or inmost heaven, constitute the higher heavens; while the remainder of those in the second or middle heaven, together with those who are in the first or outmost heaven, constitute the lower heavens. The "four animals" signify specifically the third or inmost heaven, and the "four and twenty elders" the second or middle heaven that is in conjunction with the third or inmost; thus together they signify the higher heavens. Respecting the intermediate angels, called celestial-spiritual and spiritual-celestial, and the conjunction of the third heaven with the second by these, see Arcana Coelestia 1577, 1824, 2184, 4047, 4286, 4585, 4592, 4594, 6435, 6526, 8787, 8802, 9671).