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In Genesis 2:24, this signifies to separate from the internal man. (Arcana Coelestia 160)
In Genesis 44:22, this signifies to separate truth from spiritual good, which cannot be done, or else the church perishes. (Arcana Coelestia 5812-5813)
In Genesis 50:8, this signifies that the goods of innocence and charity, interior and exterior, remained in the inmost parts of man. (Arcana Coelestia 6532)