'Wilderness' signifies something with little life in it, as described in the internal sense in Luke 1:80 'Wilderness' signifies somewhere there is no good because there is no truth. 'Wilderness,' as in Jeremiah 23:10, signifies the Word when it is adulterated.

(Odkazy: Arcana Coelestia 1927)

4481. 'And carry on trade throughout it' means in doctrine. This is clear from the meaning of 'carrying on trade throughout the land' as entering into cognitions of good and truth, dealt with in 4453, and so into doctrine, for doctrine contains and teaches those cognitions.