In Leviticus 20:20; 25:49, the "uncle" signifies consanguinity: that the good and truth of the rational are not to be conjoined, as in a marriage, but as brother and sister. (Arcana Coelestia 2524)

In Jeremiah 32:8, 9, 12, this signifies something spiritual having relation to regeneration, its beginning and its end. (Arcana Coelestia 755[3], Apocalypse Explained 166)