Genesis 27:37

³⁷ And Isaac answered and said unto Esau, Behold, I have made him thy lord, and all his brethren have I given to him for servants. And with grain and new wine have I sustained him. And what then shall I do for thee, my son?

Wrath

'Great wrath,' as in Revelation 12:12, signifies hatred against the new church.

'Wrath,' as in Genesis 49:7, signifies aversion from truth.