It is common in the Bible for people to "rise up," and it would be easy to pass over the phrase as simply describing a physical action. But in fact it represents an elevation in spiritual state, moving to a more internal frame of mind closer to the Lord. Often it has to do with understanding a new or important idea; we "rise up" to a state of greater perception and enlightenment. Obviously context is crucial to the exact meaning of the phrase in a given passage -- it matters greatly who it is that is rising up, and why.

2546. 'What have you done to us, and what sin have I committed against you?' means reproving Himself for having thought in this fashion. This becomes clear from the emotion and the strong feeling which these words contain, referred to just above in 2543, on account of the fact that the rational and the factual wished to rise up and enter in, and in so doing to share in the doctrine of faith, which is Divine.