Genesis 28:12

¹² And he saw in his sleep a ladder standing upon the earth, and the top thereof touching heaven: the angels also of God ascending and descending by it;

Genesis 24:5

⁵ The servant answered: If the woman will not come with me into this land, must I bring thy son back again to the place, from whence thou camest out?

'Isaac' signifies the Lord's interior self and His divine rational in reference to divine good.