In Genesis 42:21, anguish signifies the distress of the Lord's internal man when it was alienated. (Arcana Coelestia 5470)

In Exodus 6:9, anguish signifies a state near to despair. (Arcana Coelestia 7217)

In Psalm 119:143, being in a state of anguish refers to when a person does not perceive the Lord as present. (Arcana Coelestia 5962)

In Isaiah 30:6, anguish signifies the state of the church in which there is no good of charity or truth of faith. (Arcana Coelestia 6544[1])