'Look not back behind thee,' as in Genesis 19:17, means that Lot, who represents the good of charity, should not look to matters of doctrine. 'To look up,' is to look to celestial things. In Genesis 18:22, looking signifies thinking because seeing denotes understanding.

(Reference: Arcana Coelestia 2245)

3866. Ex sensu interno verborum, quae Leah dixit de Reubene cum natus, nempe ex his, ‘vidit Jehovah afflictionem meam quia nunc amabit me vir meus’, constare potest quid Ecclesiae ‘Reuben’ aut tribus a Reubene nominata, significet, quod nempe id quod primum regenerationis est, seu quod primum est cum homo fit Ecclesia, quod nempe sit verum doctrinae per quod ad bonam vitae pervenire possit.