Say
As with many common verbs, the meaning of “to say” in the Bible is highly dependent on context. Who is speaking? Who is hearing? What is it about? Is it a command, a message, an apology, instruction? All these things enter into the meaning of “say.” In general, though, “saying” has to do with sharing truth at various levels -- from the most exalted power people can have to perceive the Lord's desires directly to the most basic of orders issued to people at their lowest.
Harm
To do “harm” in the Bible specifically refers to attacks and injury by evil and falsity against what is good and true. The reverse is never the case, because the Lord -- who is love itself -- never wishes harm on anyone, and we can never wish harm on anyone when our motivations come from the love and wisdom that come to us from the Lord. People do harm to themselves, though, when they turn away from the Lord, and the evil will attack and harm each other. So there is hurt in the world, but it comes from evil.